Table 2.
Probability of IRG DEG enrichment at distinct stages of multiple sclerosis.
| IRG DEG | All IRG | IRG DEG % | Global DEG | Expressed Global genes | Global DEG % | Chi square (Yate’s correction) | P-value | Z-score | |
|---|---|---|---|---|---|---|---|---|---|
| CIS | 250 | 2385 | 10.48 | 1010 | 10314 | 9.79 | 1.570 | 0.2101 | 1.29 |
| RR-MS | 220 | 2385 | 9.22 | 764 | 10314 | 7.4 | 14.59 | 0.0001 | 3.86 |
| PP-MS | 480 | 2385 | 20.12 | 2039 | 10314 | 19.76 | 0.220 | 0.6388 | 0.49 |
| SP-MS | 409 | 2385 | 17.14 | 1854 | 10314 | 17.97 | 1.366 | 0.2425 | −1.19 |
HC = Healthy controls; CIS = clinically isolated syndrome; RR-MS = Relapsing-Remitting multiple sclerosis; PP-MS = Primary progressive multiple sclerosis; SP-MS = Secondary progressive multiple sclerosis; DEG = differentially expressed genes.