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. 2017 Aug 21;7:8330. doi: 10.1038/s41598-017-08568-9

Table 2.

Grade-wise distributions of characteristics and serum biochemical values.

First grade (n = 149) Fourth grade (n = 160) Seventh grade (n = 340) P
Range Median Range Median Range Median
Homocysteine (mol/L) 5.16–13.09 7.99 1.87–22.99 8.02 3.2–27.9 9.31 <0.001a***
AST (IU/L) 15–75 25.00 14–124 23.00 11–95 20.00 <0.001a***
ALT (IU/L) 5–82 14.00 7–271 15.00 4–178 12.00 <0.001a***
TGs (mg/dL) 26–263 58.00 25–356 66.00 26–353 65.00 0.144a
Fasting blood glucose (mg/dL) 69–173 85.00 75–363 89.00 57–140 91.00 <0.001a***
Creatinine (mg/dL) 0.3–0.7 0.50 0.4–0.7 0.50 0.4–0.9 0.60 <0.001a***
Mean SD Mean SD Mean SD P
Depression 44.96 8.50 45.99 9.73 47.89 10.18 0.005b** 7 > 1
Anxiety 47.30 8.56 46.74 8.36 50.17 10.46 <0.001b*** 7 > 1,4
SBP (mmHg) 101.73 10.33 108.99 12.09 111.45 9.10 <0.001b*** 7 > 4 > 1
DBP (mmHg) 60.12 9.21 63.36 10.11 63.50 8.30 0.001b** 4,7 > 1
T-Chol (mg/dL) 172.91 29.70 175.00 30.94 159.97 27.86 <0.001b*** 1,4 > 7
HDL (mg/dL) 60.45 11.43 58.45 12.79 55.69 12.65 <0.001b*** 1 > 7
LDL (mg/dL) 100.04 26.14 100.21 24.69 90.24 23.83 <0.001b*** 1,4 > 7
Urea N (mg/dL) 12.36 2.65 12.00 2.92 11.47 2.60 0.002b** 1 > 7
BMI (kg/m2) 19.05 4.02 20.98 4.59 20.52 4.00 <0.001b*** 4,7 > 1
nd % nd % nd % P
ECG <0.001c***
  Normal 80 58.4 105 70 314 92.4
  Arrhythmia 15 10.9 7 4.7 8 2.4
 Other abnormality 42 30.7 38 25.3 18 5.3
Sex (male) 76 51.0 88 55.0 182 53.5 0.776c
Fruit frequency (times/week) 0.020c*
  0–5 30 21.3 27 17.8 91 26.8
  6–10 55 39.0 66 43.4 114 33.6
  11–15 37 26.2 24 15.8 78 23.0
  >16 19 13.5 35 23.0 56 16.5
Vegetable frequency (times/week) 0.110c
  0–5 17 11.8 11 7.2 50 14.7
  6–10 30 20.8 36 23.5 76 22.4
  11–15 56 38.9 59 38.6 99 29.2
  >16 41 28.5 47 30.7 114 33.6

*P < 0.05; **P < 0.01; ***P < 0.001.

aResults from a Kruskal–Wallis test.

bResults from a one-way analysis of variance test.

cResults from a chi-square test.

dTotal counts may vary because of missing data.

AST, aspartate transaminase; ALT, alanine aminotransferase; TGs, triglycerides; SBP, systolic blood pressure; DBP, diastolic blood pressure; T-Chol, total cholesterol; HDL, high-density lipoprotein; LDL, low-density lipoprotein; ECG, electrocardiogram.