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Affinity and rate constants of TRAIL-Trimer, TRAIL-Fc and native TRAIL with DR5-Fc.
| Analyte | Receptor | Kon (1/Ms) | Koff (1/s) | KD (M) |
|---|---|---|---|---|
| TRAIL-Fc | DR5-Fc | 9.25E + 03 | 1.71E-04 | 1.85E-08 |
| native TRAIL | DR5-Fc | 1.75E + 05 | 4.6E-05 | 2.63E-10 |
| TRAIL-Trimer | DR5-Fc | 8.10E + 04 | <1.0E-07 | <1.0E-12 |
