Table 1.
Baseline demographic and laboratory characteristics of patients on PD categorized according to time-averaged serum HS-CRP levels
| Time-averaged serum HS-CRP (mg/L) |
Total (n=335) 9.18±12.28 (0.25–109.47) |
Lower tertile (n=112) 1.38±0.67 (0.25–2.65) |
Middle tertile (n=111) 5.07±1.69 (2.66–8.55) |
Upper tertile (n=112) 21.05±15.16 (8.58–109.47) |
P-value |
|---|---|---|---|---|---|
| Male | 115 (34.3) | 37 (33.0) | 41 (36.9) | 37 (33.0) | 0.778 |
| Age (years) | 48.7±13.5 | 46.4±13.7 | 47.0±12.6 | 52.6±13.5 | 0.001 |
| Body mass index (kg/m2) | 22.5±3.6 | 21.5±3.1 | 22.6±3.2 | 23.4±4.1 | <0.001 |
| DM | 54 (16.1) | 10 (8.9) | 14 (12.6) | 30 (26.8) | 0.001 |
| CAD | 10 (3.0) | 1 (0.9) | 2 (1.8) | 7 (6.3) | 0.042 |
| CHF | 21 (6.3) | 7 (6.3) | 9 (8.1) | 5 (4.5) | 0.533 |
| Stroke | 18 (5.4) | 2 (1.8) | 7 (6.3) | 9 (8.0) | 0.101 |
| SLE | 13 (3.9) | 3 (2.7) | 6 (5.4) | 4 (3.6) | 0.561 |
| Liver cirrhosis | 18 (5.4) | 4 (3.6) | 4 (3.6) | 10 (8.9) | 0.123 |
| Hepatitis B | 43 (12.8) | 9 (8.0) | 12 (10.8) | 22 (19.6) | 0.025 |
| Hepatitis C | 21 (6.3) | 11 (9.8) | 5 (4.5) | 5 (4.5) | 0.164 |
| PD duration (months) | 52.7±41.3 | 46.3±40.1 | 50.6±38.8 | 61.1±43.9 | 0.022 |
| PD system (Fresenius) | 7 (2.1) | 1 (0.9) | 2 (1.8) | 4 (3.6) | 0.362 |
| PD modality (APD) | 64 (19.1) | 19 (17.0) | 24 (21.6) | 21 (18.8) | 0.672 |
| Daily dwell volume (L) | 8.89±1.96 | 8.49±1.94 | 9.20±2.03 | 8.99±1.86 | 0.020 |
| Icodextrin use | 176 (52.5) | 54 (48.2) | 60 (54.1) | 62 (55.4) | 0.522 |
| Nutrineal use | 13 (3.9) | 3 (2.7) | 4 (3.6) | 6 (5.4) | 0.574 |
| Dialysate dextrose (%) | 1.86±0.48 | 1.72±0.44 | 1.90±0.47 | 1.96±0.50 | 0.001 |
| Dialysate calcium (2.5 mEq/L) | 139 (41.5) | 46 (41.1) | 44 (39.6) | 49 (43.8) | 0.614 |
| Residual urine | 223 (67.0) | 89 (80.2) | 76 (68.5) | 58 (52.3) | <0.001 |
| White blood cell count (1,000/µL) | 7.553±2.649 | 6.685±2.354 | 7.619±2.190 | 8.688±2.832 | <0.001 |
| Hemoglobin (g/dL) | 10.18±1.53 | 10.37±1.60 | 10.33±1.34 | 9.85±1.60 | 0.017 |
| Platelet count (1,000/µL) | 249.27±78.29 | 225.60±62.67 | 259.50±82.69 | 262.80±82.96 | >0.001 |
| Albumin (g/dL) | 4.01±0.42 | 4.05±0.40 | 4.03±0.42 | 3.94±0.44 | 0.117 |
| Total cholesterol (mg/dL) | 204.2±50.3 | 203.3±47.1 | 205.0±50.7 | 204.4±53.3 | 0.966 |
| HDL (mg/dL) | 47.2±14.9 | 54.0±15.1 | 44.5±13.8 | 42.9±13.5 | <0.001 |
| LDL (mg/dL) | 120.1±40.9 | 120.2±40.5 | 120.2±43.4 | 120.0±39.3 | 0.999 |
| Triglycerides (mg/dL) | 183.2±106.1 | 146.5±79.2 | 204.5±119.7 | 197.8±106.3 | <0.001 |
| HbA1c (%) | 5.61±0.92 | 5.43±0.91 | 5.59±0.88 | 5.80±0.95 | 0.011 |
| Blood urea nitrogen (mg/dL) | 58.84±17.97 | 61.24±17.48 | 56.32±19.05 | 58.93±17.14 | 0.123 |
| Creatinine (mg/dL) | 11.27±2.96 | 11.32±3.03 | 11.49±3.19 | 10.99±2.63 | 0.432 |
| Uric acid (mg/dL) | 6.83±1.27 | 6.68±1.14 | 6.79±1.30 | 7.04±1.35 | 0.096 |
| Calcium (mg/dL) | 9.99±1.03 | 9.79±1.09 | 10.05±1.12 | 10.14±0.84 | 0.027 |
| Phosphorus (mg/dL) | 4.99±1.32 | 4.94±1.18 | 4.99±1.27 | 5.03±1.51 | 0.883 |
| Aluminum (µg/dL) | 0.90±0.89 | 0.79±0.75 | 0.79±0.79 | 1.11±1.08 | 0.015 |
| iPTH (pg/mL) | 336.5±383.8 | 299.6±345.0 | 347.1±376.6 | 362.9±426.1 | 0.439 |
| Transferrin saturation (%) | 27.2±12.4 | 28.8±12.0 | 27.6±10.7 | 25.4±14.1 | 0.115 |
| Ferritin (µg/L) | 326.0±531.6 | 225.8±349.0 | 304.3±432.4 | 446.4±720.0 | 0.010 |
Note: Continuous variables are given as mean ± standard deviation, and categorical variables, as number (percentage).
Abbreviations: HS-CRP, high-sensitivity C-reactive protein; DM, diabetes mellitus; CAD, coronary artery disease; CHF, congestive heart failure; SLE, systemic lupus erythematosus; APD, automated peritoneal dialysis; HDL, high-density lipoprotein; LDL, low-density lipoprotein; HbA1c, glycated hemoglobin; iPTH, intact parathyroid hormone.