Table 3.
Clinical outcomes in the PD patients categorized according to time-averaged serum HS-CRP levels
| Time-averaged serum HS-CRP (mg/L) |
Total (n=335) 9.18±12.28 (0.25–109.47) |
Lower tertile (n=112) 1.38±0.67 (0.25–2.65) |
Middle tertile (n=111) 5.07±1.69 (2.66–8.55) |
Upper tertile (n=112) 21.05±15.16 (8.58–109.47) |
P-value |
|---|---|---|---|---|---|
| Outcomes | <0.001 | ||||
| Death | 52 (15.5) | 6 (5.4) | 15 (13.5) | 31 (27.7) | <0.001 |
| Infection | 31 (9.3) | 3 (2.7) | 9 (8.1) | 19 (17.0) | 0.001 |
| Cardiovascular event | 10 (3.0) | 1 (0.9) | 4 (3.6) | 5 (4.5) | 0.261 |
| Malignancy | 5 (1.5) | 0 (0) | 1 (0.9) | 4 (3.6) | 0.072 |
| Sudden death | 6 (1.8) | 2 (1.8) | 1 (0.9) | 3 (2.7) | 0.606 |
| Transfer to HD | 100 (29.9) | 32 (28.6) | 35 (31.5) | 33 (29.5) | 0.885 |
| PD peritonitis | 63 (18.8) | 19 (17.0) | 23 (20.7) | 21 (18.8) | 0.773 |
| Membrane failure | 8 (2.4) | 3 (2.7) | 5 (4.5) | 0 (0) | 0.086 |
| EPS | 16 (4.8) | 4 (3.6) | 5 (4.5) | 7 (6.3) | 0.634 |
| Abdominal operation | 7 (2.1) | 4 (3.6) | 2 (1.8) | 1 (0.9) | 0.362 |
| Mechanical complication | 2 (0.6) | 1 (0.9) | 0 (0) | 1 (0.9) | 0.607 |
| ADL disability | 4 (1.2) | 1 (0.9) | 0 (0) | 3 (2.7) | 0.172 |
| Transplantation | 12 (3.6) | 2 (1.8) | 8 (7.2) | 2 (1.8) | 0.043 |
| Technique survival | 171 (51.0) | 72 (64.3) | 53 (47.7) | 46 (41.1) | 0.002 |
| Cardiovascular event(s) | 91 (27.2) | 20 (17.9) | 29 (26.1) | 42 (37.5) | 0.004 |
| Infection episode(s) | 221 (66.0) | 64 (57.1) | 73 (65.8) | 84 (75.0) | 0.019 |
| Malignancy | 35 (10.4) | 9 (8.0) | 8 (7.2) | 18 (16.1) | 0.057 |
| Urothelial cell carcinoma | 11 (3.3) | 3 (2.7) | 4 (3.6) | 4 (3.6) | 0.908 |
| Renal cell carcinoma | 7 (2.1) | 2 (1.8) | 3 (2.7) | 2 (1.8) | 0.859 |
| Breast cancer | 4 (1.2) | 1 (0.9) | 0 (0) | 3 (2.7) | 0.172 |
| Thyroid cancer | 4 (1.2) | 1 (0.9) | 1 (0.9) | 2 (1.8) | 0.779 |
| Hepatocellular carcinoma | 2 (0.6) | 0 (0) | 0 (0) | 2 (1.8) | 0.135 |
| Gynecologic cancer | 2 (0.6) | 1 (0.9) | 0 (0) | 1 (0.9) | 0.607 |
| Prostate cancer | 1 (0.3) | 1 (0.9) | 0 (0) | 0 (0) | 0.368 |
| Lung cancer | 1 (0.3) | 0 (0) | 0 (0) | 1 (0.9) | 0.368 |
| Rectal cancer | 2 (0.6) | 0 (0) | 0 (0) | 2 (1.8) | 0.135 |
| Brain giloma | 1 (0.3) | 0 (0) | 0 (0) | 1 (0.9) | 0.368 |
| EPS | 16 (4.8) | 4 (3.6) | 5 (4.5) | 7 (6.3) | 0.634 |
Note: Categorical variables are given as number (percentage).
Abbreviations: PD, peritoneal dialysis; HS-CRP, high-sensitivity C-reactive protein; HD, hemodialysis; ADL, activities of daily living; EPS, encapsulating peritoneal sclerosis.