Table 1.
Differences between patients with and without history of self-reported ON
| Eye with history of ON
|
P-value | ||
|---|---|---|---|
| Yes | No | ||
| Number | 23 | 44 | |
| Age (years) | 49.3 (39.0–62.8) | 50.0 (33.1–72.6) | 0.72 |
| Sex (% male) | 39.1 | 22.7 | 0.16 |
| Time since onset of MS (years) | 12 (9–15) | 13 (9–15) | 0.08 |
| Visual acuity (ETDRS letters) | 87 (63–93) | 86 (76–93) | 0.50 |
| Ishihara (number of errors) | 0 (0–16) | 0 (0–16) | 0.50 |
| Intraocular pressure (mmHg) | 15 (7–26) | 15 (10–23) | 0.82 |
| CRT (μm) | 228 (199–274) | 230 (179–290) | 0.46 |
| RNFL | |||
| Superior (μm) | 111 (74–124) | 108 (70–142) | 0.39 |
| Inferior (μm) | 109 (73–131) | 113 (91–150) | 0.04* |
| Temporal (μm) | 56 (32–84) | 67 (43–95) | 0.01* |
| Nasal (μm) | 83 (56–115) | 81 (54–101) | 0.90 |
| Mean (μm) | 87 (61–105) | 92 (70–113) | 0.07 |
| CRT/RNFLmean ratio | 2.6 (2.0–3.8) | 2.5 (1.8–3.7) | 0.12 |
Notes: Continuous data presented as median (with range), and categorical data presented as percentage. Mean values of left and right eye used for patients with history of no or bilateral ON. Values of eye with ON were used for patients with history of unilateral ON.
*
Statistically significant (P<0.05).
Abbreviations: CRT, central retinal thickness; ETDRS, Early Treatment Diabetic Retinopathy Study; MS, multiple sclerosis; ON, optic neuritis; RNFL, retinal nerve fiber layer.