Table 2.

Alpha coefficients and corresponding adjusted effect and sample sizes.

					Reproducibility-adjusted				Additional n required
	Cronbach’s α coefficients				Cohen’s d (0.50)				(power = 0.80)
	All	HC	T2DM	AD	All	HC	T2DM	AD	All	HC	T2DM	AD
Motor thresholds
RMT monophasic	0.97	0.94	0.98	0.98	0.50	0.49	0.50	0.50	0	1	0	0
RMT biphasic	0.94	0.83	0.96	0.98	0.49	0.48	0.49	0.50	1	3	1	0
AMT biphasic	0.90	0.77	0.95	0.85	0.49	0.47	0.49	0.48	2	4	1	3
Baseline MEPs
Monophasic	0.78	0.67	0.50	0.72	0.47	0.45	0.42	0.46	4	7	14	6
Biphasic	0.63	0.19	0.11	0.90	0.44	0.32	0.28	0.49	9	44	69	2
Paired-pulse measures
SICI	0.71	0.68	0.78	0.81	0.46	0.45	0.47	0.47	6	7	4	4
LICI	0.50	0.98	0.17	0.88	0.42	0.50	0.31	0.48	14	0	49	2
ICF	0.25	0.11	0.58	0.85	0.35	0.28	0.43	0.48	34	69	10	3
Post-iTBS measures
5 min post-iTBS	0.41	0.34	0.24	0.55	0.40	0.38	0.34	0.43	19	24	34	12
10 min post-iTBS	0.18	0.19	0.12	0.81	0.32	0.32	0.29	0.47	46	44	64	4
20 min post-iTBS	0.45	0.56	0.57	0.59	0.41	0.43	0.43	0.43	16	11	11	10
30 min post-iTBS	0.29	0.31	0.20	0.53	0.36	0.37	0.33	0.42	28	26	41	12
40 min post-iTBS	0.47	0.22	0.35	0.65	0.41	0.34	0.38	0.45	15	38	23	8
50 min post-iTBS	0.17	0.30	0.16	0.17	0.31	0.37	0.31	0.31	48	27	49	11
Maximum facilitation	0.45	0.02	0.44	0.56	0.41	0.17	0.40	0.43	16	234	17	11
Area under-the-curve
0–20 min post-iTBS	0.46	0.20	0.33	0.82	0.41	0.33	0.37	0.47	15	42	24	3
0–50 min post-iTBS	0.48	0.40	0.41	0.64	0.41	0.39	0.40	0.44	15	19	19	8

HC, healthy controls; T2DM, Type-2 diabetes mellitus; AD, Alzheimer’s disease; RMT, resting motor threshold; AMT, active motor threshold; MEPs, motor evoked potentials; SICI, short-interval intracortical inhibition; LICI, long-interval intracortical inhibition; ICF, intracortical facilitation.