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. 2017 Aug 21;8:992. doi: 10.3389/fimmu.2017.00992

Figure 1.

Figure 1

Clinical and histological features of dermatomyositis (DM). (A) Gottron’s sign: erythematous scaly papules over the metacarpophalangeal joints. (B) «V sign» in a white European male patient with DM. (C) Poikiloderma (i.e., erythema, atrophy, variable pigmentary changes) on the upper trunk of an African Caribbean female patient with DM. (D) Typical centripetal flagellate erythema affecting the upper trunk of a male patient with DM. (E,F) Periungual erythema and telangiectatic capillary loops in patients with DM. (G–I) Histological feature of a Gottron’s papule. (G) Slight hyperkeratosis, basal cell vacuolar degeneration, upper dermal edema, and perivascular inflammatory cell infiltrate with enlarged capillaries (HES staining, ×20). (H) DM interface dermatitis with vacuolar changes of the basal cell layer, perivascular inflammatory cell infiltrate with capillary dilatation, endothelial cell turgescence, and pigmentary incontinence (HES staining, ×40). (I) Positive alcian-blue staining attesting dermal mucin deposits (×20).