Table 2.

Odds ratios for the presence of white matter hyperintensities

Parameters for sarcopenia		Men			Women
		Odds ratio	95% CI	P	Odds ratio	95% CI	P
Thigh muscle CSA/1 SD	n	603			902
	No adjustment	0.63	0.52–0.77	<.0001	0.81	0.69–0.96	.015
	Adjustment 1	0.74	0.54–099	.046	0.88	0.70–1.11	.29
	Adjustment 2	0.75	0.55–1.01	.059	0.89	0.70–1.14	.30
Skeletal muscle mass/1 SD	n	609			909
	No adjustment	0.65	0.53–0.79	<.0001	0.67	0.56–0.80	<.0001
	Adjustment 1	0.80	0.60–1.08	.15	0.73	0.57–0.93	.01
	Adjustment 2	0.82	0.60–1.11	.20	0.73	0.57–0.94	.01

CI, confidence interval.

Odds ratios for the presence of white mater hyperintensities, stratified by increase in sarcopenic indices (by 1 SD).

Adjustment 1: adjusted for age, body mass index, systolic blood pressure, triglyceride levels, total cholesterol levels, high‐density lipoprotein cholesterol levels, glucose levels, immunoreactive insulin levels, use of antihypertensive drugs, antidyslipidemic drugs, antidiabetic drugs, current smoking, alcohol intake, physical activity (1 + 2 + 3 + 4).

Adjustment 2: Further adjustment for brachial–ankle pulse wave velocity.

White matter hyperintensity was defined as periventricular hyperintensity grade ≥ 2 and/or deep subcortical white matter hyperintensity grade ≥ 3. One SD of thigh muscle CSA was 18.92 cm² for men and 13.49 cm² for women, and that of skeletal muscle mass was 3.14 kg for men and 2.02 kg for women.