Table 2.

CHRNA7 interacting protein

S. No.	Name	Function	Disease	Pathway
1	CHRNA4	Neurodevelopment protein involved in differentiation and neurogenesis	Autosomal dominant nocturnal frontal lobe epilepsy	Neuroactive ligand-receptor interaction, Cholinergic synapse and nicotine addiction
2	CHRNB4, CHRNA3, CHRNA2, CHRNA5, CHRNA6	AChR responds by an extensive change in conformation that leads to opening of an ion-conducting channel across the plasma membrane	Frontal lobe epilepsy	Neuroactive ligand-receptor interaction
3	AKT1	AKT is responsible of the regulation of glucose uptake by mediating insulin-induced translocation	Neurological diseases	Rap1 signaling pathway, Ras signaling pathway
4	JAK2	Janus kinase 2; non-receptor tyrosine kinase involved in various processes such as cell growth, development, differentiation or histone modifications	Polycythemia vera, Budd-Chiari syndrome	Chemokine signaling pathway Jak-STAT signaling pathway
5	PICK1	Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors	Central nervous system disease and nervous system disease	Transmission across chemical synapses and transmission across chemical synapses