Table 4.
WHO grade II adult diffuse gliomas
| Astrocytoma histology | Oligodendroglioma histology | Oligoastrocytoma or ambiguous histology | |
|---|---|---|---|
| IDHmt, 1p19q-nondel, ATRX loss | Diffuse astrocytoma, IDHmt | Diffuse astrocytoma, IDHmt | Diffuse astrocytoma, IDHmt |
| IDHmt, 1p19q-codel, ATRX intact | Oligodendroglioma, IDHmt & 1p19q codel | Oligodendroglioma, IDHmt & 1p19q codel | Oligodendroglioma, IDHmt & 1p19q codel |
| IDHwt | Diffuse astrocytoma, IDHwt | Oligodendroglioma, NOS | Diffuse astrocytoma, IDHwt |
IDH: isocitrate dehydrogenase.