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. 2017 Aug 23;37(34):8077–8091. doi: 10.1523/JNEUROSCI.0313-17.2017

Figure 8.

Figure 8.

Comparison of NMJ transmission data collected under voltage-clamp (mEPC and eEPC) and current-clamp (mEPPnorm and eEPPcorr) from the same control (cntrl) and R6/2 fibers. A, mEPCs (p = 0.003, t test), but not mEPPnorm (p = 0.071, t test), were significantly lower in R6/2 compared with control fibers. B, Similarly, eEPCs (p = 6.4 × 10−5, t test), but not eEPPcorr (p = 0.45, t test), were significantly lower in R6/2 compared with control fibers. C, Estimates of quantal content from voltage-clamp (QC) and current-clamp (QCIC) were lower for R6/2 compared with control (p = 0.008 and p = 0.02, respectively, t test). *Indicates a significant difference compared with control NMJs. Error bars are ±SEM.