Figure 9.

Var(QC) versus QC plot for estimating the probability of release (p_rel) and number of vesicle release sites (n). Experimental Var(QC) and QC data superimposed on two theoretical models (parabolas and straight lines). The parabolas model Var(QC) and QC while varying p_rel and holding n constant. Straight lines model Var(QC) and QC while varying n and holding p_rel constant. The lower QC (vesicle release per impulse) in R6/2 compared with control fibers was primarily due to a lower n. Error bars are ±SEM.