Table 1.
Membrane and action potential properties of ERK:D2 MSNs
| Group | IR (MΩ) | RMP (mV) | Rheo (pA) | Thresh (mV) | Amp (mV) | H.W. (ms) | MaxAPs |
|---|---|---|---|---|---|---|---|
| D2R Control | 126 ± 19 | −79.6 ± 2.7 | 161 ± 20 | −38.8 ± 1.3 | 72.0 ± 3.2 | 0.87 ± 0.07 | 45.1 ± 3.3 |
| D2R Erk:D2 | 115 ± 15 | −76.2 ± 4.7 | 315 ± 68* | −29.4 ± 4.5 | 52.8 ± 7.7* | 0.87 ± 0.10 | 25.6 ± 7.8* |
| D1R Control | 87 ± 12 | −85.6 ± 2.0 | 204 ± 16 | −38.5 ± 2.2 | 73.1 ± 4.6 | 0.87 ± 0.06 | 37.7 ± 2.9 |
| D1R Erk:D2 | 73 ± 6 | −76.9 ± 4.6 | 252 ± 18 | −33.9 ± 2.1 | 68.3 ± 4.4 | 0.87 ± 0.05 | 36.7 ± 2.4 |
Basic membrane properties and action potential properties in D2R-MSNs and D1R-MSNs recorded during intrinsic excitability experiments.
IR, Input resistance; RMP, resting membrane potential; Rheo, rheobase; Thresh, action potential threshold; Amp, action potential amplitude; H.W., half-width; MaxAPs, maximum number of action potentials for any current step.
*p < 0.05 versus control neurons.