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. 2017 Aug 21;8:540. doi: 10.3389/fphar.2017.00540

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Copyright © 2017 Rahman, Abdul Murad, Mollah, Jamal and Harun.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Heatmap from microarray gene expression analyses showing the differentially expressed genes in the A549 and NCI-H1299cell lines. (A) Shows differentially expressed genes in both cell lines at48h post–NFIX shRNAs transfection as compared to the non-silenced samples. (B) T-test, LIMMA and ANOVA were used to identify differentially expressed genes between NFIX silencing and non-silencing in the A549 and NCI-H1299cell lines. In total, 18 genes were identified as differentially expressed between both cell lines (^∗with Benjamini-Hochberg adjustment with p-value < 0.05).