Table 1.
Case reports of drug-induced macular edema caused by taxane
| Case (first author [ref.]) | Age, years | Affected side | Symptom | Treatment | Treatment time to recovery | Causing agent | Bevacizumab |
|---|---|---|---|---|---|---|---|
| Joshi [3] | 63 | bilateral | decreased vision |
cessation | 6 weeks | PTX | no |
| Ham [13] | 57 | bilateral | decreased vision |
cessation, intravitreal bevacizumab |
6 weeks | PTX | yes |
| Kuznetcova [9] | 64 | bilateral | decreased vision |
cessation | 4 weeks | PTX | yes |
| Murphy [7] first case | 65 | bilateral | decreased vision |
cessation, NSAIDs, topical steroids |
3 weeks | nab-PTX | yes |
| Murphy [7] second case | 58 | bilateral | decreased vision |
cessation | 3 weeks | nab-PTX | yes |
| Smith [8] | 56 | bilateral | decreased vision |
cessation | 4 weeks | nab-PTX | no |
| Matsuoka [16] | 39 | bilateral | decreased vision |
STTA, cessation | 11 months, not fully recovered | nab-PTX | no |
| Teitelbaum [4] | 53 | bilateral | blurred vision |
cessation | 6 weeks | DTX | no |
| Telander [5] | 60 | bilateral | decreased vision |
cessation, acetazolamide |
16 weeks | DTX | no |
| Enzsoly [6] | 45 | bilateral | decreased vision |
cessation, topical nepafenac | 5 weeks | DTX | no |
PTX, paclitaxel; nab-PTX, nanoparticle albumin-bound paclitaxel; DTX, docetaxel; NSAID, nonsteroidal anti-inflammatory drug; STTA, sub-Tenon triamcinolone acetonide injection.