Skip to main content
. 2017 Jul 12;37(4):BSR20170771. doi: 10.1042/BSR20170771

Figure 2. Effect of K+ on G-quadruplex folding kinetics.

Figure 2

(A) CD spectra of G-quadruplexes in 100 mM KCl buffer. Inset, G-quadruplex hybrid-1 type topology with fluorescent labels at the two ends of the DNA strand. (B) Time-courses of the fluorescence intensity of FAM after the unfolded G-quadruplex DNA were rapidly mixed with different concentrations of KCl at room temperature (23°C). The solid lines are double-exponential fits of the data. (C) Folding amplitudes of the fast and the slow phases, and the total amplitude. (D) Folding rates of the fast and the slow phases.