Figure 4.

(a) Reduction of B. bacteriovorus HD100 by whole human serum. A serially diluted preparation of B. bacteriovorus HD100 was inoculated into whole human serum and viability measured over a 72 h period. (b) Reduction of K. pneumoniae concentration by whole human serum. A serially diluted preparation of K. pneumoniae was inoculated into whole human serum and viability measured over a 72 h period by Miles and Misra. (c) Model simulations of B. bacteriovorus reduction in human serum for three different initial conditions. Solid line show simulation result whilst the circles show the experimental results (replicated from panel a). Parameter values are given in Supplementary Table S2, in the supplementary materials.