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. 2017 Aug 21;7:9018. doi: 10.1038/s41598-017-09432-6

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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PNG+aFGF+ChABC treatment improves urodynamic recovery. (a–c) Representative urodynamic recordings at 40 weeks after SCI. (a’-c’) Compressed view of bladder pressure recordings. Asterisks mark expanded void shown below. (a”-c”) Expanded time points from a’-c’. Grey box denotes the time between opening peak pressure (OPP) and closing peak pressure (CPP). Black dots denote EUS bursting. (d) Scatter plot of EUS bursting over three void cycles in relation to bladder contractions for individual animals. Grey box denotes the time interval between OPP and CPP (0–100%). (e) Percentage of animals displaying EUS bursting. (f) Average number of EUS bursts per void. (g) Percentage of EUS bursts between OPP and CPP of bladder contractions. (h) Average residual bladder volume following a void. (i) Bladder weight 40 weeks post-injury. (j) The bladder volume needed to initiate the first void. (k) The maximal pressure reached during a void. n = 6 per group. *p < 0.05, **p < 0.01. One-way ANOVA, Fisher’s Least Significant Difference post-hoc test. Data represent mean ± S.E.M.