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. 2017 Aug 21;7:8360. doi: 10.1038/s41598-017-08641-3

Table 1.

Onset temperature and Tm of the BsAb (CD3×HER2) and it’s parental mAbs.

Antibody Onset Tm
CD3×HER2 BsAb 58.5°C 67.5°C
Trastuzumab 60.9°C 69.6°C
Anti-CD3 mAb 57.6°C 66.8°C