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. 2017 Aug 22;7:9073. doi: 10.1038/s41598-017-08290-6

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Short-term time trace of the ionic current while the homopolymer or block copolymer remained in the nanopore. Typical time trace of the ionic current for 1 sec while (a) poly(dA)_5.3k, (b) [(dT)₂₅-(dC)₂₅]_m, (c) [(dA)₅₀-(dC)₅₀]_m, and (d) [(dT)₂₅-(dC)₂₅-(dA)₅₀]_m remained in the nanopore. Each applied voltage was 100 mV. Each current signal was filtered at 2 kHz. The values of the ionic-current blockades at the intensity peaks in each histogram were (a) 118 pA; (b) 148 pA and 197 pA (shaded blue and green, respectively); (c) 72 pA and 176 pA (shaded red and blue, respectively); and (d) 98 pA, 173 pA, and 222 pA (shaded red, blue and green, respectively).