Table 3.

Genotypic association of rs12143842 with IVT.

Region	Case			Control			Model	OR (95% CI)	P	OR (95% CI)#	P #	P $
	CC	CT	TT	CC	CT	TT
Northern	143	114	20	310	331	87	Co-dominant
	(51.62)	(41.16)	(7.22)	(42.58)	(45.47)	(11.95)	CT vs CC	0.75 (0.56~1.00)	0.049	0.65 (0.43~0.98)	0.041	0.045
							TT vs CC	0.50 (0.29~0.84)	0.009	0.54 (0.27~1.10)	0.090	0.082
							Dominant
							TT + CT vs CC	0.69 (0.53~0.92)	0.010	0.63 (0.42~0.93)	0.021	0.027
							Recessive
							TT vs CT + CC	0.57 (0.35~0.95)	0.032	0.67 (0.34~1.33)	0.251	0.227
							Additive	0.72 (0.58~0.90)	0.003	0.70 (0.51~0.95)	0.023	0.022
Central	137	96	26	301	313	73	Co-dominant
	(52.90)	(37.07)	(10.04)	(43.81)	(45.56)	(10.63)	CT vs CC	0.67 (0.50~0.91)	0.011	0.65 (0.47~0.88)	0.006	0.004
							TT vs CC	0.78 (0.48~1.28)	0.328	0.76 (0.46~1.25)	0.275	0.301
							Dominant
							TT + CT vs CC	0.69 (0.52~0.93)	0.013	0.67 (0.50~0.90)	0.007	0.008
							Recessive
							TT vs CT + CC	0.94 (0.59~1.51)	0.792	0.93 (0.58~1.49)	0.753	0.732
							Additive	0.80 (0.64~1.00)	0.046	0.78 (0.62~0.98)	0.030	0.025
Combined	280	210	46	611	644	160	Co-dominant
	(52.24)	(39.18)	(8.58)	(43.18)	(45.51)	(11.31)	CT vs CC	0.71 (0.58~0.88)	0.002	0.68 (0.54~0.86)	0.001	<0.001
							TT vs CC	0.63 (0.44~0.90)	0.011	0.65 (0.44~0.96)	0.030	0.023
							Dominant
							TT + CT vs CC	0.69 (0.57~0.85)	<0.001	0.67 (0.54~0.84)	<0.001	0.001
							Recessive
							TT vs CT + CC	0.74 (0.52~1.04)	0.081	0.78 (0.54~1.13)	0.192	0.195
							Additive	0.76 (0.65~0.89)	<0.001	0.76 (0.64~0.90)	0.001	0.002

^#Adjusted by age, sex.

^$Empirical P values were derived by performing 1,000 Monte–Carlo simulations.