Table 1.
Item | Score |
---|---|
Underlying disease associated with DIC* | 2 |
More than one of the following clinical manifestations independent of original diseases: | 1 |
(1) Bleeding; | |
(2) Organ dysfunction; | |
(3) Microcirculatory disorder. | |
Platelet count (×109/L) | |
<80 | 2 |
<100 and ≥80, or ≥50% decrease within 24 hours | 1 |
≥100 | 0 |
Prolongation of prothrombin time (PT) and activated partial thromboplastin time (APTT) (s) | |
Prolongation of PT ≥6 | 2 |
Prolongation of PT ≥3 and <6, or prolongation of APTT ≥10 | 1 |
Prolongation of PT <3 and prolongation of APTT <10 | 0 |
D-dimer (mg/L) | |
≥9 | 3 |
≥5 and <9 | 2 |
<5 | 0 |
Fibrinogen (g/L) | |
<1.0 | 1 |
≥1.0 | 0 |
Diagnosis of DIC | ≥7 |
*If underlying disease is hematological malignancy: (1) No point for bleeding; (2) 1 point for platelet count of <50 × 109/L or ≥50% decrease within 24 hours; 3) Diagnosis of DIC is ≥6.