Table 4.
Assessment of IHC staining of the clinical samples for CAP1, SHC1 and PRCP. Intensity of staining in the tissue was graded as “negative/below limit of detection” (−), “weak” (+), “medium” (++) or “strong” (+++). The respective figures are provided in Supplementary Figures 1 and 2. NA – not available.
| Group | Sample ID | Intensity of staining | |||
|---|---|---|---|---|---|
| CAP1 | SHC1 | PRCP | |||
| Cases | IgAN | 305 | +++ | +++ | ++ |
| IgAN | 313 | +++ | +++ | ++ | |
| IgAN | 315 | +++ | NA | ++ | |
| IgAN | 312 | +++ | +++ | +++ | |
| IgAN | 310 | − | +++ | +++ | |
| IgAN | 302 | ++ | + | +++ | |
| IgAN | 306 | + | +++ | ++ | |
| IgAN | 307 | + | ++ | ++ | |
| Controls | glomerular disease | 311 | − | ++ | + |
| glomerular disease | 309 | +++ | +++ | +++ | |
| glomerular disease | 303 | + | ++ | + | |
| kidney | kidney | − | + | + | |