Table 1.

Advantages and limitations of CT and Histopathology.

CT		Histopathology
Advantages	Limitations	Advantages	Limitations
Non-invasive (longitudinal studies)	Anatomical/Macroscopic	Cellular resolution	Invasive/ex vivo (sample required)
3D volume	Relies solely on density (not fibrosis specific)	Masson’s trichrome staining is fibrosis specific	Fixation and sectioning affect tissue
Clinically translatable		Tissue architecture	One slice of tissue
		Clinically translatable (biopsies)	Staining procedure