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. 2017 Aug 22;7:9114. doi: 10.1038/s41598-017-09532-3

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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The natamycin biosynthetic gene cluster (BGC) of A02 (A) and comparison analysis of the natamycin BGCs of sln, scn and pim using the MAUVE program (B). The horizontal panels depict the sln (upper), scn (middle) and pim (lower) clusters. Mean sequence similarities are proportional to the heights of the red bars, and the respective scales show the sequence coordinates in base pairs. Regions with low similarities and strain-specific regions are marked with black triangles. Arrows indicate deduced transcriptional units.