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Dose response of OM. Steady-state tensions in muscle fibers were measured in pCa 6.0 solution, with OM concentration ranging from 0.1 to 10 μM. Tension increased with increasing OM concentration up to 3.0 μM and saturated thereafter. Asterisks indicate a significant difference from untreated fibers (∗p < 0.05, ∗∗∗p < 0.001; NS, not significant). A separate set of four fibers was measured at each concentration. Data are expressed as the mean ± SE.
