Table 5.

Schedule for nicotine pharmacokinetic assessment

Day	Start of Procedure	Procedure
7	19:00–20:00a	Start of product use abstinence
	20:00–22:00	Snack
8	06:00–08:00b	Light breakfast / snack
	08:00–11:00	Start of pharmacokinetic assessment period
		• Pharmacokinetic blood draws
		• Product satisfaction questionnaire
	12:00–15:00	End of pharmacokinetic assessment period

^aFollowing completion of final 24-h urine collection period. ^bLight breakfast / snack will be completed at least 1 h prior to the start of the pharmacokinetic assessment period