Table 2.
Identified plasmid and chromosome-encoded virulence genes and other genetic features of O145:H25 and other EHEC genomes
| Strains | O145:H25 | O145:H28 | O26:H11 | O103:H2 | O111:HNM | O157:H7 | O165:H25 | ||
|---|---|---|---|---|---|---|---|---|---|
| CFSAN004176 | CFSAN004177 | RM13514 | RM13516 | 11,365 | 12,009 | 11,128 | Sakai | 2012C-4227 | |
| chromosome-encoded | |||||||||
| aidA-I | - | - | 2 (1) | 3 (3) | 2 | 2 (1) | 1 | 1 | - |
| astA | 1 | 1 | 1 | 1 | 1 | - | 1 | 1 | 1 |
| bor (iss) | 1 | 1 | 1 | - | 2 | 1 | 1 | 2 | 1 |
| eae type | β | β | γ | γ | β | ε | θ | γ | ε |
| efa1 | 2 (1) | 2 | (+/−) | 1 | 1 | 2 | 1 | (+/−) | 1 |
| ehaA | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| espI | 1 | 1 | 1 | - | - | 1 | - | - | 1 |
| gad | 1 | 1 | 1 | - | 1 | 1 | 1 | 1 | 1 |
| iee | (+/−) | (+/−) | 1 | 1 | 1 | 1 | 1 | 1 | - |
| iha | - | - | 1 | 1 | 2 | - | 1 | 1 | - |
| lpf cluster | 1 | 1 | 1 (1) | 1 | 2 | 1 | 2 | 2 (1) | 1 |
| pagC | - | - | - | 1 | - | 2 | 1 | 1 | - |
| sod (Cu/Zn) | 1 | 1 | 2 | 2 | - | 2 | 2 | 2 | 1 |
| stx genes | stx 2a | stx 2a | stx 2a | stx 2a | stx 1a | stx 1a + stx 2a | stx 1a + stx 2a | stx 1a + stx 2a | stx 1a + stx 2a |
| tir | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| plasmid-encoded | |||||||||
| cba | 1 | 1 | - | - | - | - | - | - | - |
| cma | 1 | 1 | - | - | - | - | - | - | - |
| ecf | - | - | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| ehxA subtype | E | E | C | C | C | F | C | B | C |
| espI | 1 | 1 | - | - | - | - | - | - | - |
| espP | - | - | 1 | - | - | - | (+/−) | 1 | 1 |
| katP | - | - | - | - | 1 | - | - | 1 | 1 |
| sfp | 1 | 1 | - | - | - | - | - | - | 1 |
| sta1 | 1 | 1 | - | - | - | - | - | - | - |
| stcE | - | - | - | 1 | - | 1 | - | 1 | - |
| toxB | - | - | 1 | - | 1 | - | - | 1 | - |
present (≥ 90% identity, ≥ 80% gene coverage); −, absent; (+/−), partial (≥ 90% identity, 10–80% coverage);
numbers in parentheses indicate pseudogene(s)