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. 2016 Oct 14;33(1):53–61. doi: 10.1007/s12264-016-0073-2

Fig. 7.

Fig. 7

MO-mediated Sox11a+11b knockdown suppressed optic axon regrowth in explants. A–D Representative images of retinal explants showing the outgrowth of regenerated RGC axons from control (A) and Sox11a/11b MO-treated retinas (B–D). Retinas were isolated 4 days after optic nerve transection, diced, and cultured for another 4 days before analysis of neurite outgrowth. The red fluorescence is from lissamine-tagged control or Sox11a/11b MOs (scale bar, 200 μm). E, F Quantification of axon length and density (mean ± SD, n = 6 individual fish; con-MO, control MO; **P < 0.01 compared to control).