Table 1.
Distribution of KATP channels
Subtypes of KATPchannels | Tissue expression | Migraine related structures |
---|---|---|
Kir6.2/SUR1 | Pancreas and brain | DRG, TG and TNC from rats (20–24, 26). |
Kir6.2/SUR2A | Cardiac and skeletal muscle | |
Kir6.2/SUR2B | Smooth muscle | DRG, TG, TNC, BA and MCA from rats(20–24, 26). |
Kir6.1/SUR2B | Smooth muscle | MMA from rats, pigs and human; MCA from rats and pigs; BA, DRG, TG and TNC from rats (20–24, 26). |
DRG Dorsal root ganglia, TG trigeminal ganglion, TNC trigeminal nucleus caudatus, BA basilar artery, MMA middle meningeal artery, MCA middle cerebral artery