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. Author manuscript; available in PMC: 2018 Jul 21.
Published in final edited form as: Org Biomol Chem. 2017 Jun 27;15(27):5656–5668. doi: 10.1039/c7ob01058c

Figure 1.

Figure 1

Heparan sulfate structure and biosynthesis. Respective O- and N-sulfotransferases (HS2ST, HS3ST, HS6ST, and NDST) sulfate specific sites along the HS chain (shown in bold). The purple and orange oval shapes depict protein binding sites along the HS chain. Inset: Pentasaccharide antithrombin (AT) binding sequence.