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. Author manuscript; available in PMC: 2018 Sep 1.
Published in final edited form as: Traffic. 2017 Sep;18(9):590–603. doi: 10.1111/tra.12499

Figure 7. Evolution of ENTH and VHS domains.

Figure 7

(A) Structural overlay of tENTH, tVHS, epsin1 ENTH, and GGA3 VHS domains. All four domains demonstrate a conserved structural core containing helices α1–7. (B) Phylogenetic tree of ENTH, tepsin ENTH (tENTH), VHS, and tepsin VHS-like (tVHS) domains, with ANTH domains as an outgroup.