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. Author manuscript; available in PMC: 2017 Aug 23.
Published in final edited form as: Gene Ther. 2015 Apr 23;22(7):536–545. doi: 10.1038/gt.2015.21

Figure 4.

Figure 4

(a–j) Microscopic imaging of cartilage explants 48 h after euthanasia and collection. Explants were observed under × 100 magnification with (right image) and without (left image) a fluorescent filter (excitation of 495 nm, emission of 521 nm). High dosed (scAAV2GFP) joints are shown in panels a and b, middle dosed joints are shown in c and d, and low dosed joints are shown in panels e and f. Cartilage from the joints re-injected with scAAV6GFP are shown in panels g and h. Panels i and j represent arthroscopic images 4 months following a joint injected with scAAVGFP. The bright green dots represent transduced chondrocytes within the cartilage viewed arthroscopically following injection.