Table 3.

Spearman correlations between drusen volume and retinal pigment epithelium-drusen-complex abnormal thinning volume indexed for visual acuity, cone-mediated sensitivity, and rod-intercept.

Visual Function	Drusen Volume	p-Value	RAT Volume	p-Value
Visual Acuity	0.017	0.876	0.017	0.875
Cone-mediated sensitivitya
Mean	−0.045	0.671	−0.312	0.003
Minimum	−0.053	0.616	−0.273	0.009
Maximum	−0.050	0.639	−0.328	0.002
Rod-mediated dark adaptationb	−0.003	0.979	0.280	0.023

RAT = retinal pigment epithelium-drusen-complex abnormal thinning,

^aMean sensitivity across zones 1 – 8,

^bN = 66 eyes

For the purposes of analysis, cone-mediated sensitivity was defined per subject as the average sensitivity across the 8 test targets within a 6° (1.73 mm) diameter, and also the average of each eye’s lowest sensitivity target (minimum), and the average of the eye’s highest sensitivity points for each eye (maximum). Age-adjusted N = 91 eyes (unless otherwise noted).