Table 3.
A comparison of survival between ex-smokers and non-smokers in the step-by-step multivariate models
| HR | 95% CI | p-value | |
|---|---|---|---|
| Univariate | |||
| Ex-smoker | Reference | ||
| Non-smoker | 0.64 | 0.42 – 0.97 | 0.037 |
| Model containing DLco% | |||
| Ex-smoker | Reference | ||
| Non-smoker | 0.79 | 0.50 – 1.24 | 0.306 |
| Dlco% | 0.97 | 0.95 – 0.98 | <0.001 |
| Model containing CPI | |||
| Ex-smoker | Reference | ||
| Non-smoker | 0.75 | 0.48 – 1.17 | 0.197 |
| CPI | 1.04 | 1.02 – 1.06 | <0.001 |
| Model containing DLco % and age | |||
| Ex-smoker | Reference | ||
| Non-smoker | 0.82 | 0.52 – 1.27 | 0.371 |
| Dlco% | 0.96 | 0.95 – 0.98 | <0.001 |
| Age at diagnosis | 1.05 | 1.02 – 1.08 | 0.001 |
| Model containing CPI and age | |||
| Ex-smoker | Reference | ||
| Non-smoker | 0.79 | 0.51 – 1.23 | 0.292 |
| CPI | 1.05 | 1.03 – 1.07 | <0.001 |
| Age at diagnosis | 1.06 | 1.03 – 1.09 | <0.001 |
| Model containing DLco %, age and gender | |||
| Ex-smoker | Reference | ||
| Non-smoker | 1.32 | 0.76 – 2.30 | 0.324 |
| Dlco% | 0.96 | 0.95 – 0.98 | <0.001 |
| Age at diagnosis | 1.06 | 1.03 – 1.09 | <0.001 |
| Gender - female | Reference | ||
| male | 2.35 | 1.24 – 4.45 | 0.009 |
| Model containing CPI, age and gender | |||
| Ex-smoker | Reference | ||
| Non-smoker | 1.22 | 0.71 – 2.10 | 0.472 |
| CPI | 1.05 | 1.03 – 1.07 | <0.001 |
| Age at diagnosis | 1.07 | 1.04 – 1.10 | <0.001 |
| Gender - female | Reference | ||
| male | 2.22 | 1.18 – 4.18 | 0.013 |
HR hazard ratio, CI confidence interval, DLco diffusion capacity of carbon monoxide, CPI composite physiologic index