Table 2.
TCGA | TCGA | METABRIC | METABRIC | |
---|---|---|---|---|
Gene | % Breast Cancers with Mutations | Types of Mutations | % Breast Cancers with Mutations | Types of Mutations |
Shh | 1.5% | Amplifications | 2.1% | Amplifications |
Ihh | 1% | Amplifications, deep deletions | 0.2% | Amplifications |
Dhh | 0.2% | Amplifications | 0.3% | Amplifications |
Ptch1 | 1.8% | Missense, with a few amplifications and deep deletions | 0.6% | Amplifications |
Ptch2 | 1.8% | Amplifications, with a few deletions, truncations, and missense | 1.3% | Amplifications |
Smo | 1.2% | Amplifications | 1.4% | Amplifications |
Hhip | 0.7% | Amplifications | 0.7% | Amplifications |
Gli1 | 1.5% | Amplifications and missense | 0.6% | Amplifications |
Gli2 | 1.5% | Missense | 0.3% | Amplifications |
Gli3 | 2.6% | Amplifications and missense | 2.4% | Amplifications |