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. 2017 Aug 22;18:41. doi: 10.1186/s12865-017-0225-9

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — TOFA rebalanced immunocytes in BWF1. (a) Percentages of naïve/inactive T or T_EM cells from each mouse group. (b) Percentages of CD4⁺CD69^high or CD4⁺CD25^high T cells from each mouse group. (c, left) Percentages of T_reg cells from each mouse group. (c, right) Foxp3 expression in kidneys of BWF1. Each represents [TOFA (n = 13–15); TOFA + DEXA (n = 15); DEXA (n = 8); and control (n = 13–14)]. *p < 0.05, **p < 0.01, ***p < 0.001 and ****p < 0.0001 (vs. control mice). Freq. of Total (%): frequency of total splenocytes; T_EM: effector/memory T; T_reg: regulatory T