Table 2.
Changes in serum creatinine or creatinine clearance from baseline according to renal function (baseline creatinine clearance)
| Renal function [19] (CrCL range [mL/min]) |
Change in serum creatininea (µmol/L) | Change in CrCLb (ml/min) |
|---|---|---|
|
|
|
|
| Median (range) | Median (range) | |
| Normal or mild impairment (≥50); n=271 | 14.0 (−53.0, 154) | −8.84 (−77.4, 55.6) |
| Moderate impairment (30–50); n=67 | 17.0 (−26.0, 98.1) | −5.59 (−19.3, 9.38) |
| Severe impairment (<30); n=3 | 19.0 (11.5, 53.0) | −3.47 (−6.94, −3.42) |
a
Highest serum creatinine at any visit minus baseline serum creatinine.
b
Lowest CrCL at any visit minus baseline CrCL.
CrCL, creatinine clearance