Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Comparison of antiproliferative potency and cell apoptosis induction of 2,3-dehydrosilybins in the PC-3 cell model
| Compound | IC50 (μM) | Apoptotic cell population | Ref. |
|---|---|---|---|
| 2,3-dehydrosilybin (2) | 9.45 ± 0.56 | 14% (treated with 60 μM) | 14 |
| 3-O-propyl-2,3-dehydrosilybin (4) | 1.71 ± 0.45 | 8% (treated with 60 μM) | 14 |
| 7-O-ethyl-2,3-dehydrosilybin (3) | 3.25 ± 0.31 | 66% (treated with 50 μM) | 15 |
| 5-O-heptyl-2,3-dehydrosilybin (35) | 4.61 ± 0.64 | 87% (treated with 50 μM) | New data |
