Figure 2. vic1 is not a classical MHC-I or MHC-II gene.

Mice were infected with MMTV via fostering by infected females and screened for anti-virus Abs three months later. (B6 × I) F1 and (B6^vic1i/ix I) F1 mice were used as negative and positive controls for Ab production, respectively. Means are derived from combined data from 4 independent experiments. (MHC-II^−/− × I) F1 mice include 20 (H2-Ab^−/− × I) F1 and 10 (MHC-II del × I) F1 mice. I, I/LnJ mice. Significance was calculated using an unpaired t test.