Table 3.

Lipid parameters and major cardiovascular events in IDEAL

Variables		Baseline	12 week	1 year	2 year	3 year	4 year	5 year
N	SIMV	4445	4371	4290	4168	4033	3930	775
	ATV	4435	4334	4198	4099	3985	3861	758
LDL cholesterol (mmol/L)	SIMV	3.14 (0.01)	2.71 (0.01)	2.64 (0.01)	2.68 (0.01)	2.75 (0.01)	2.68 (0.01)	2.58 (0.02)
	ATV	3.15 (0.01)	2.01 (0.01)	2.05 (0.01)	2.12 (0.01)	2.22 (0.01)	2.16 (0.01)	2.07 (0.03)
	HR	1.14 (1.07–1.20)	1.09 (1.03–1.16)	1.12 (1.05–1.19)	1.13 (1.06–1.20)	1.10 (1.03–1.18)	1.08 (1.01–1.16)	1.06 (0.91–1.25)
Non-HDL cholesterol (mmol/L)	SIMV	3.87 (0.02)	3.41 (0.01)	3.33 (0.01)	3.36 (0.01)	3.43 (0.01)	3.37 (0.01)	3.26 (0.03)
	ATV	3.90 (0.02)	2.59 (0.01)	2.63 (0.01)	2.70 (0.01)	2.79 (0.01)	2.74 (0.01)	2.67 (0.03)
	HR	1.15 (1.08–1.21)	1.10 (1.04–1.17)	1.15 (1.08–1.22)	1.18 (1.11–1.25)	1.12 (1.04–1.20)	1.11 (1.03–1.19)	1.07 (0.91–1.25)
Apolipoprotein B (g/L)	SIMV	1.19 (0.0)	1.05 (0.0)	1.07 (0.0)	1.03 (0.0)	1.06 (0.0)	1.09 (0.0)	1.08 (0.01)
	ATV	1.19 (0.0)	0.80 (0.0)	0.84 (0.0)	0.82 (0.0)	0.86 (0.0)	0.90 (0.0)	0.91 (0.01)
	HR	1.15 (1.09–1.22)	1.13 (1.06–1.19)	1.17 (1.10–1.24)	1.18 (1.11–1.26)	1.16 (1.08–1.24)	1.13 (1.05–1.21)	1.07 (0.91–1.26)
Estimated apoB (g/L)	SIMV	1.01 (0.0)	0.90 (0.0)	0.87 (0.0)	0.88 (0.0)	0.90 (0.0)	0.89 (0.0)	0.86 (0.01)
	ATV	1.02 (0.0)	0.69 (0.0)	0.70 (0.0)	0.72 (0.0)	0.74 (0.0)	0.73 (0.0)	0.71 (0.01)
	HR	1.15 (1.09–1.21)	1.11 (1.04–1.17)	1.14 (1.08–1.21)	1.17 (1.10–1.24)	1.12 (1.05–1.20)	1.11 (1.04–1.20)	1.07 (0.91–1.25)

Data are expressed as mean (SE) or HR per 1-SD (95% CI)

Adjusted for age and sex

ATV atorvastatin, SIMV simvastatin