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. 2017 Aug 8;16:343–354. doi: 10.1016/j.nicl.2017.08.006

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© 2017 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 6. — Computational experiment. FC strengths were calculated after performing simulations with manipulated local bifurcation parameters (within range − 0.05 and − 0.15) based on healthy control subjects. A The Euclidean distance between simulated FC strengths and group averaged empirical FC strengths of PAD (green), MCI (blue) and AD (red) subjects. Dashed lines indicate the minimum distance between simulated FC strengths and group averaged empirical FC strengths of each group, colored accordingly. B The simulated coherence with respect to manipulated local bifurcation parameters. C The simulated metastability with respect to manipulated local bifurcation parameters. Gray shadings show the standard deviations of each parameter across subjects. Colored dots indicate the average empirical coherence and metastability of PAD (green), MCI (blue) and AD (red) groups. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)