Fig. 4.

Exo2 exhibits inhibitory activity of prostate tumor growth in vivo. a, b When PC3-derived xenografts had been established, the SCID mice were randomly divided into four groups for treatment with vehicle or the indicated concentrations of Exo2 (n = 5/group). Tumor growth was measured by tumor volume (a), tumor weight and mouse body weight (minus tumor) at the end of the experiment was calculated (b). c, d The xenografts were removed these mice for Western blot with the indicated antibodies. Representative result of Western blot is shown in (c) and quantitative data are shown in (d). **p < 0.01