Table 4.
Groups | CAT | SOD | GST | GR | GPx | GSH |
---|---|---|---|---|---|---|
(U/mg protein) | (U/mg protein) | (mU/mg protein) | (U/mg protein) | (U/mg protein) | (μmoles/mg protein) | |
Control | 372.1 ± 7.4a | 11.0 ± 1.1a | 184.3 ± 9.6a | 28.8 ± 1.1a | 3.0 ± 0.2a | 72.8 ± 3.1a |
BPH | 28.0 ± 3.7d | 1.2 ± 0.2c | 7.6 ± 3.0d | 9.8 ± 0.3c | 1.5 ± 0.1c | 33.4 ± 3.2c |
Finasteride | 399.9 ± 38.5b | 11.1 ± 0.2a | 141.8 ± 11.7ab | 24.6 ± 0.4a | 2.7 ± 0.1a | 67.6 ± 3.2ab |
AG 100 | 35.4 ± 10.0d | 6.0 ± 0.5b | 74.0 ± 10.1c | 19.9 ± 1.8b | 1.9 ± 0.3b | 34.7 ± 2.1c |
AG 250 | 170.5 ± 10.9c | 7.9 ± 0.8b | 71.0 ± 23.8c | 25.8 ± 2.3a | 2.7 ± 0.1a | 37.4 ± 0.9c |
AG 500 | 232.0 ± 11.2b | 11.2 ± 0.2a | 172.2 ± 22.1a | 26.5 ± 0.6a | 2.7 ± 0.1a | 62.0 ± 2.6b |
Data express the mean ± S.E. The letters in the columns indicate statistical differences by Duncan’s multiple range test (p < 0.05). Control: Normal rat supplied with tap water, BPH: Castrated rat supplied with tap water, AG 100: Castrated rat supplied with AG 100 mg/kg of BW daily, AG 250: Castrated rat supplied with AG 250 mg/kg of BW daily, AG 500: Castrated rat supplied with AG 500 mg/kg of BW daily. CAT: Catalase, SOD: Superoxide dismutase, GST: Glutathione S-transferase, GR: Glutathione reductase, GPx: Glutathione peroxidase, GSH: Glutathione