Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Aug 23;12(8):e0183724. doi: 10.1371/journal.pone.0183724

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2017 Hosokawa et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

PMC Copyright notice

Fig 1 — (A) Averaged mass spectrum obtained from the cancer epithelial area of the non-recurrence case (No. 1). (B) Averaged mass spectrum from the cancer epithelial area of the recurrence case (No. 9). Regions of interest set in cancer epithelial areas are presented as black squares in the hematoxylin and eosin -stained images, Scale bar = 1000 μm. (C) Averaged signal intensities of m/z 732.5 and 706.5 in the recurrence group (n = 3) were significantly higher than those in the non-recurrence group (n = 6, P = 0.024* and 0.048*, respectively). Averaged signal intensity of m/z 806.5 in the recurrence group (n = 3) was significantly lower than that in the non- recurrence group (n = 6, P = 0.048*) No significant differences occurred between the two groups related to the signal intensity at m/z 734.5 (P >0.5). The mean value of the averaged signal intensity at m/z 732.5 in the recurrence group was two times higher than that in the non-recurrence group. The lowest averaged signal intensity at m/z 732.5 in the recurrence group (No. 8) was 1.5 times higher than the highest in the non-recurrence group (No. 5). (D) Compared with the non-recurrence group, the ratio of the signal intensity of m/z 732.5 to that of m/z 806.5 was significantly higher in the recurrence group (P = 0.024*).* The mean value of the ratio of the signal intensity at m/z 732.5 to that at m/z 806.5 in the recurrence group was 2.7 times higher than that in the non-recurrence group. The highest ratio of the signal intensity at m/z 732.5 to that at m/z 806.5 in the recurrence group (No. 7) was 1.8 times higher than the lowest in the non-recurrence group (No. 6). P < 0.05. NS: not statistically significant.