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. 2017 Aug 23;18:652. doi: 10.1186/s12864-017-4063-1

Table 2.

The Relative synonymous codon usage (RSCU) patterns of polymerase genes of EIVs and their host species

Amino acid Codon PB2 PB1 PA Horse Donkey Dog Amino acid Codon PB2 PB1 PA Horse Donkey Dog
Phe UUU 0.98 0.63 1.22 0.83 0.88 0.82 Ser UCA 2.2 1.58 1.18 0.80 0.83 0.81
UUC 1.02 1.38 0.77 1.17 1.12 1.16 UCG 0.43 0.17 0.15 0.34 0.24 0.38
Leu UUA 0.55 0.72 1.08 0.33 0.24 0.35 AGU 0.76 0.68 1.25 0.86 1.10 0.89
UUG 1.45 1.29 0.92 0.72 0.82 0.68 AGC 1.24 1.32 0.74 1.48 1.27 1.56
CUU 1.16 0.65 1.35 0.73 0.80 0.67 Arg AGA 1.4 1.57 1.13 1.30 1.49 1.20
CUC 0.88 0.79 1.05 1.32 1.63 1.25 AGG 0.6 0.43 0.87 1.32 1.86 1.32
CUA 0.95 1.11 0.66 0.34 0.18 0.37 CGU 0.63 0.00 0.57 0.55 0.49 0.46
CUG 1 1.44 0.92 2.56 2.33 2.45 CGC 0.99 0.48 1.13 1.15 0.79 1.26
Ile AUU 1.31 0.91 1.24 0.92 0.58 0.96 CGA 0.98 1.91 2.1 0.61 0.74 0.67
AUC 0.52 0.85 0.83 1.66 1.95 1.61 CGG 1.4 1.61 0.17 1.08 0.62 1.31
AUA 1.18 1.24 0.93 0.42 0.47 0.45 Cys UGU 0.01 1.19 0.59 0.89 0.62 0.85
Val GUU 0.76 0.91 0.96 0.60 0.64 0.58 UGC 1.99 0.81 1.4 1.11 1.38 1.10
GUC 0.66 1.12 0.63 1.08 1.42 1.1 His CAU 1.4 1.11 0.92 0.81 0.89 0.78
GUA 1.18 1.08 1.04 0.35 0.29 0.42 CAC 0.6 0.89 1.07 1.19 1.11 1.22
GUG 1.4 0.89 1.34 1.97 1.65 1.98 Gln CAA 1.25 1.24 1.25 0.52 0.84 0.50
Pro CCU 1.1 1.13 0.39 1.19 0.83 1.08 CAG 0.75 0.76 0.74 1.48 1.16 1.46
CCC 0.96 0.75 0.85 1.38 1.60 1.47 Asn AAU 1.2 1.15 0.97 0.84 0.66 0.87
CCA 1.79 1.66 2.16 0.97 1.06 1.05 AAC 0.8 0.85 1.02 1.16 1.34 1.12
CCG 0.14 0.47 0.58 0.45 0.51 0.51 Lys AAA 1.37 1.32 1.33 0.79 0.79 0.79
Thr ACU 0.83 1.07 0.77 0.94 0.82 0.89 AAG 0.63 0.89 0.67 1.21 1.21 1.13
ACC 0.93 0.85 1.11 1.58 1.77 1.58 Asp GAU 1.15 1.27 1.25 0.83 0.84 0.86
ACA 1.85 1.89 2 0.96 0.79 1.05 GAC 0.85 0.73 0.74 1.17 1.16 1.09
ACG 0.39 0.19 0.1 0.52 0.61 0.53 Glu GAA 1.36 1.34 1.16 0.76 0.84 0.79
Ala GCU 0.94 1.03 1.26 1.05 1.20 1 GAG 0.64 0.66 0.83 1.24 1.16 1.23
GCC 0.93 0.94 0.81 1.72 1.74 1.78 Gly GGU 0.7 0.74 0.84 0.65 0.87 0.65
GCA 1.79 1.75 1.44 0.77 0.77 0.81 GGC 0.67 0.5 0.49 1.43 1.42 1.45
GCG 0.35 0.29 0.48 0.45 0.30 0.47 GGA 1.99 1.53 1.7 0.95 0.85 1.02
Tyr UAU 0.76 0.96 1.23 0.75 0.63 0.79 GGG 0.64 1.23 0.96 0.97 0.86 1.05
UAC 1.24 1.04 0.76 1.25 1.37 1.15
Ser UCU 0.53 0.68 1.38 1.09 1.10 1.09
UCC 0.84 1.57 1.27 1.43 1.46 1.52

Over- (RSCU ≥1.6) and under-represented (RSCU ≤0.6) codons are displayed in bold and italics, respectively