Skip to main content
. 2017 Aug 23;12(8):e0183712. doi: 10.1371/journal.pone.0183712

Fig 2. Effects of 3OTPCA on cell viability and DNA fragmentation.

Fig 2

(A) Percentage of viable cells in U937 cells treated with 0–80 μM 3OTPCA for 24 h. Cell viability was monitored using a CCK-8 assay. (B) Morphological change of nuclei was monitored by DAPI staining and fluorescence microscopy at 400× magnification. U937 cells were treated with various concentrations of 3OTPCA for 24 h. (C) DNA fragmentation in U937 cells treated with 3OTPCA for 24 h at the concentration indicated. (D) DNA fragmentation in U937 cells treated with 40 μM 3OTPCA for 3–24 h. (E-F). DNA fragmentation in Jurkat (E) and Molt-4 cells (F) treated with 3OTPCA for 24 h at the concentration indicated. The data represent the mean ± SD (N = 5). **p < 0.01 vs. CT (Student`s t-test).