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. 2017 Aug 23;12(8):e0183712. doi: 10.1371/journal.pone.0183712

Fig 7. Changes in the expression of UPR proteins, phospho-p38 MAPK, and other apoptotic proteins in U937 cells treated with 40 μM 3OTPCA (3OT) or 500 nM thapsigargin (Tg) for the time indicated.

Fig 7

(A) Time-course analysis of UPR protein expression and p38 MAPK phosphorylation in response to 3OT or Tg. (B) Dose-dependent analysis of caspase-8 cleavage and Bcl family protein expression in cells 24 h after treatment with 3OTPCA. Changes in the expression of these proteins were determined by western blot analysis.