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. 2017 Aug 23;12(8):e0183689. doi: 10.1371/journal.pone.0183689

Fig 3. CD147 gene knockdown in A375 cells affected many gene translation pathways, thus leading to the differential expression of hundreds of genes.

Fig 3

(A) Heatmap representing the expression levels of genes; red (normal) and green (siCD147) colors indicate the up- and down-regulated genes. Transcriptome analysis demonstrated 67 up-regulated and 115 down-regulated genes in A375 cells transfected with siCD147. (B) Several genes referred to in A were shown to be up- or down-regulated in A375 cells by RT-PCR The result was consistent with the transcriptome analysis.